By contrast, histologic evidence of capsular or parenchymal liver fibrosis was entirely absent in all animals that received either CTGF or TGF-β alone, and focal evidence of trace capsular fibrosis without parenchymal fibrosis was seen in only two of eight animals that received FG-3019 (Figure 3B). This evidence concerns the gene TGFB1 and Hepatic fibrosis.