Overweight/obese patients with CAD, apart from the decreased plasma adiponectin levels, had decreased AdipoR1 and AdipoR2 protein surface levels compared to patients without CAD, while they did not show any difference with respect to the levels of AdipoR1 and AdipoR2 mRNA (Figure 2A and 2B). This evidence concerns the gene ADIPOR2 and coronary artery disorder.