The four lentiviral pGIPZ-C2GnT1-shRNA vectors, the PLKO.1-C2GnT-shRNA vector, the scrambled pGIPZ-shRNA vector, and the empty PLKO.1 control vector were tested for silencing of the C2GnT1 gene in LS174T colon carcinoma and HepG2 hepatic carcinoma cells. This evidence concerns the gene GCNT1 and colon carcinoma.