SHH and omphalocele: We revealed a possibleassociation between the degree of omphalocele phenotype and pubic diastasisphenotype (Fig. 3B–D,B'–D').In addition, mutants genetically rescued from omphalocele (Gli3Xt/+;Alx4Lst/Lst; Shh+/−) did form thepubic symphysis and normal midline muscle structures (Fig. 3I; data not shown).