APOE and Alzheimer disease: Using the same selection criteria, frontal and temporal lobe samples from the AD brain showed alternative promoter usage in eleven genes (ACAP3, ARGLU1, CHD3, KIF5A, LENG8, MAPK3, NR1D1, PDE1B, PIP5K2B, RPH3A, WDR47) and three genes (APOE, KIF5A, PP2R4), respectively.