Vasa and colleagues first reported an increase in EPCs (CD34+/KDR+) and CACs out to 28 days in 40 patients with CAD.[33] Most recently, these results were replicated in a small cohort of patients initiated on Atorvastatin therapy, yielding a doubling of CD45dim/CD34+/KDR+ cells at four weeks.[34] While neither of these studies were randomized or had control groups for comparison, their results are very similar to those observed in the current study. The gene discussed is KDR; the disease is coronary artery disorder.