CCR9 and Crohn ileitis: Although antibody blockade of CCL25/CCR9 interactions ameliorated early, but not late, SAMP1/Yit chronic murine ileitis [32], it would be very interesting to test whether the CCR9 antagonist CCX282-B and/or CCR9-deficiency in the SAMP1/Yit ileitis model can ameliorate small intestinal chronic inflammation as well.