PRPF8 and retinitis pigmentosa 1: The genetic complexity of RP has been highlighted by the discovery of RP mutations not only in PRPF3 but also in other pre-mRNA splicing genes (PRPF31 for RP11 and PRPC8 for RP13) [10], [16], [17], [18]; these splicing genes function not only in the retina but also throughout the human body [12], [17], [18], [19].