The genes that appeared in the seesaw modules have been reported to be involved in developmental processes; for example, in the ZBTB16-CD81-IFITM1 module of membrane proteins, CD81 may play an important role in the regulation of lymphoma cell growth [13] and acts as the receptor for some viruses [14], and IFITM1 has been implicated in the control of cell growth [15]. The gene discussed is CD81; the disease is lymphoma.