However, in diabetic state, lipoprotein lipase is not activated due to insulin deficiency, resulting in hypertriglyceridemia[23] and insulin deficiency is also associated with hypercholesterolemia due to metabolic abnormalities.[24] In our study also, the diabetic rats showed hypercholesterolemia and hypertriglyceridemia and the treatment with plant extract significantly decreased both cholesterol and triglyceride levels. This evidence concerns the gene LPL and familial hypercholesterolemia.