In concordance with the gene expression-based IHC subtypes defined in Western BC case series [5, 22, 26], clustering based on the five tested IHC markers outlined a hormone receptors-positive/luminal-like cluster and a hormone receptors-negative cluster with basal CKs (CK5/6, CK17) and Her-2/neu. This evidence concerns the gene NR4A1 and breast cancer.