AR and Familial prostate cancer: It was notable that the WPMY-AR cells were morphologically indistinguishable from parental or control transduced (WPMY-Vec) cells and that their relative growth rate (in the presence or absence of androgen) was not significantly affected by AR overexpression, especially since AR is known to affect prostate cancer cell growth, either when it is expressed endogenously or exogenously [26], [27].