Although glutamate levels in the entire hippocampal formation of sdy−/− mice remain unaltered compared with those of sdy+/+ mice [15], the expression levels of dysbindin-1 reduced in the DGiml of schizophrenia cases while those of the vesicular glutamate transporter (VGluT-1), a glutamate terminal marker, increased [7], indicating the abnormal glutamate transmission in the DGiml in schizophrenia patients (Figure 4). This evidence concerns the gene SLC17A7 and schizophrenia.