CHKA and neoplasm: Choline kinase (CK) activity is increased in many tumours (Ramirez de Molina et al, 2002; Gallego-Ortega et al, 2009) and is a link to cell-cycle regulation (Ramirez de Molina et al, 2008) through MAPK and PI3K/AKT signalling (Chua et al, 2009; de Souza et al, 2009; Yalcin et al, 2010).