TNFSF15 and colitis: Even though sustained expression of Tl1a in T- or APC did not result in gross macroscopic gut inflammation or colitis symptoms as measured by DAI (weight loss, fecal occult blood or loose stool) for up to 1 year, there were histologically determined inflammation as evidenced by blunting of the small intestinal villi, hyperplasia of goblet and Paneth cells and increased LPMC infiltrate.