KRAS and hepatocellular carcinoma: In contrast, toxicity of both cleavable zymoxins was enhanced upon treatment of full NS3-4A expressing Huh7.5 cells, demonstrating that NS3 expression is sufficient for sensitizing hepatoma-derived Huh7.5 cells to these toxins and further emphasizes the potential of these engineered toxins in eradication of NS3 expressing liver cells.