We analyzed liver mRNA from the same mice and found differential expression of 11 genes (FDR P-value <0.05); however, these expression changes were modest; the largest change was a 1.6-fold downregulation of “similar to hepatocellular carcinoma-associated gene TD26.” The other 10 genes had fold changes below 1.2. This evidence concerns the gene ANGPTL8 and hepatocellular carcinoma.