Additionally, consistent with what has been found in other studies [27], [28], miR-210 (a well-established miRNA gene that can be induced under hypoxia conditions in many solid cancers in a HIF-1a- and VHL-dependent manner) was also found to be significantly overexpressed in all of the ccRCC samples in our study. This evidence concerns the gene VHL and nonpapillary renal cell carcinoma.