However, patients bearing mutant p53 tumours without p53γ isoform expression had a high risk of recurrence and subsequent high risk of death (HR = 7.21 and HR = 11.23, respectively) compared with patients bearing wild-type p53 tumours (Figure 2; Kaplan-Meier log-rank test: χ2 = 18.33, 1 df, P < 0.001; and χ2 = 20.70, 1 df, P < 0.001, respectively). The gene discussed is TP53; the disease is neoplasm.