TP53 and cancer: Interestingly, p53 mutation status was not associated with cancer recurrence or death in the p53γ-positive cohort (P = 0.579 and P = 0.282, respectively; BLR) (Table 2, and Table S3 in Additional file 1), despite the greater proportion of grade 3 cancers with p53 mutations (61.5%; 16 of 26) in the p53γ-positive cohort compared with the p53γ-negative cohort (25.7%; 9 of 35).