Variables included were: baseline Hb, as lower Hb at the start of the malaria transmission season has been shown to be associated with anaemia during clinical malaria [8]; Hb S, C, and alpha-thalassaemia, as variant Hb is known to be protective against severe malaria and Hb S has been shown to delay time to first clinical malaria event [9-12], and these variables could also affect the risk of anaemia. This evidence concerns the gene GSTM1 and anemia.