NR4A1 and neoplasm: There are only a few case reports or small series on the topic available, but the overall lesson learned from these cases is that signs and symptoms can be significantly aggravated antepartum or post-partum and may mimic more common conditions such as hyperemesis gravidarum, eclampsia or puerperal psychosis.[29, 30, 42] due to either (1) maternal metabolic changes causing fluid retention, vascular engorgement and edema or (2) accelerated tumor growth due to hormonal receptor expression.