Results showed that MDDCs with AG genotype had significantly higher TNFα production than those with AA genotype at 24 and 48 hr post-infection (303.51±66.75 pg/mL vs. 143.97±68.80 pg/mL and 202.35±19.35 pg/mL vs. 73.00±9.55 pg/mL; p = 0.021 and 0.002, respectively; Fig 3A). Here, TNF is linked to infection.