It includes (a) improved insulin sensitivity (Facchini et al, 1994; Lazarus et al, 1997); (b) reduction in oxidative stress as alcoholic beverages contain anti-oxidant phenolic compounds and can remove oxidised carcinogenic agents, reduce lipid peroxidation and cell proliferation, and promote apoptosis (Gago-Dominguez et al, 2002; Lee et al, 2006; Lowrance et al, 2010); and (c) the diuretic effect of alcohol, which may help to control hypertension (Lee et al, 2006). This evidence concerns the gene INS and Hypertension.