The immunophenotyping of the lymphocytes, especially CD4+ T cells from peripheral blood is being used to assess the extent of immune dysfunction in the primary and secondary immunodeficiency, chronic infectious diseases and various cancers such as Hodgkin’s disease, lymphoma, etc. The clinical applications of immunophenotyping of CD4+ T cells include the monitoring of disease progression in HIV infection3, 4, diagnosis of immunodeficiency disorders5, 6, evaluation of immune-mediated diseases7, and the assessment of immune reconstitution following stem cell transplantation8. This evidence concerns the gene CD4 and cancer.