These include use of monoclonal antibodies and immunohistochemistry,11 denaturing high-performance liquid chromatography (DHPLC),27 capillary electrophoresis of multiplex PCR products,28 and also fluorescence resonance energy transfer (FRET).29 In our study, the conformation-sensitive gel electrophoresis (CSGE) technique was used to screen AML patients with NPM1 mutations. The gene discussed is NPM1; the disease is acute myeloid leukemia.