The observed discordance amongst the polygamous partners may be due to polygamous partnerships formed after HIV infection, as in the case of partnership 1 where the third wife (PP1-F3) is discordant with a subtype A/A/A virus (env-C2V3/gag-p24/pol-IN) as opposed to the other two wives' and husband's subtype D/D/D viruses (env-C2V3/gag-p24/pol-IN). The gene discussed is CD44; the disease is HIV infectious disease.