HSD has no significant effect on blood glucose level, that result was in accordance with Fukuchis et al. [35] who reported that rats fed a sucrose diet for 4 wks had significantly larger visceral fat pads and hypertriglyceridemia, however, neither plasma glucose nor insulin levels were significantly higher, while hyperglycemia and insulin resistance occur after 20 wks of feeding HSD. The gene discussed is INS; the disease is hypertriglyceridemia.