In this study, the immunohistochemical staining intensity of both radixin and moesin was examined in tissue microarrays of normal donor prostates (NDP), benign prostatic hyperplasia (BPH), high-grade prostatic intraepithelial neoplasia (HGPIN), prostatic adenocarcinoma (PCa), and normal tissue adjacent to prostatic adenocarcinoma (NAC). This evidence concerns the gene MSN and benign prostatic hyperplasia.