Consistently, the sensitivity analysis restricted to TP and TN (Additional file 2) depicted the same figures with stronger links, which argued for a causative role of CHIKV in the pathogenesis of symptoms (this time including hearing loss, P = 0.016), and indirectly for subjectivity in FP, NKP, FN, and NKN subsets. The gene discussed is FN1; the disease is hearing loss disorder.