We went on to show that the target of 968 is glutaminase C (GAC), a specific carboxy-terminal splice variant form of kidney-type glutaminase (GLS1), which is one of two known mammalian glutaminase enzymes (the other being the “liver-type” or GLS2), found in kidney and a variety of other tissues including a number of types of cancer cells [29]. The gene discussed is GLS; the disease is cancer.