LEP and metabolic syndrome: An international cross-sectional study of 788 HIV-infected adults recruited at 32 centers has studied the metabolic syndrome prevalence using International Diabetes Federation (IDF) and U.S. National Cholesterol Education Program Adult Treatment Panel III (ATPIII) criteria, relative to body composition (whole-body dual-energy X-ray absorptiometry and abdominal computed tomography), lipids, glycemic parameters, insulin resistance, leptin, adiponectin, and C-reactive protein (CRP) [3].