Although we revealed that there was no obvious change in the biological properties of subcutaneous fat, endocrine disorders in other visceral fat such as abdominal fat could not be excluded in non-obese CAD patients, giving that Cheng KH et al. demonstrated that the tissue level of adiponectin in abdominal fat was significantly lower than epicardial fat in CAD patients [28]. Here, ADIPOQ is linked to endocrine system disorder.