The main clinical findings observed from disease onset to the time of molecular analysis (baseline) were noted in 11 children carrying TNFRSF1A structural mutations (defined as TRAPS patients), 20 children with the R92Q substitution, and 64 patients with PFAPA, as shown in Table 2. The gene discussed is TNFRSF1A; the disease is TNF receptor 1-associated periodic fever syndrome.