TGFBR1 and colorectal carcinoma: Consistent with this analysis, no differences were identified between MECC and BCCS CRC patients when ASE was treated as a binary variable (P=0.20), suggesting that ethnic origin (Ashkenazi Jewish and Caucasian) and the source of biological material assessed (uncultured blood lymphocytes and normal colon mucosae) do not have a major influence on TGFBR1 ASE assessment.