In Figure 3B, the level of IL-6 in culture supernatants from cells preincubated with IFNα2 followed by TLR3 stimulation with poly(I:C) was significantly higher than that in SSc dermal fibroblasts preincubated in media alone followed by poly(I:C) stimulation (P = 0.002). The gene discussed is IFNA2; the disease is systemic sclerosis.