Similar to the studies with Becn1+/− mice, ATG7flox/flox-Lyz-Cre mice were susceptible to toxoplasmosis despite upregulation of IFN-γ, TNF-α and NOS2 mRNA (Figure 7G) and the generation of T. gondii-specific T cell response (Figure 7H). The gene discussed is LYZ; the disease is toxoplasmosis.