ATG16L1 and inflammatory bowel disease: Most recently, genome-wide association studies and subsequent replication studies have provided further insights into IBD pathogenesis by identification and confirmation of susceptibility genes such as the interleukin-23 receptor (IL23R) [11], [12], SLC22A4/5[13] and ATG16L1[14] (autophagy-related 16-like 1) gene.