Among the down-regulated genes, NKAIN1 was selected for RT-PCR validation, along with two other genes known to be involved in cancer biology: TUSC3 and TPD52, that were among the 28 most strongly down-regulated probes (FC≥2) (Table S3) and that were also among the most predictive genes in PAM analysis with a lower FC threshold of 2.5 (data not shown). The gene discussed is TPD52; the disease is cancer.