No significant difference in serum FGF-21 levels was observed between CHD patients with hypertension (462.2 ng/l, [59.1–2614.9], n = 97) and CHD patients without hypertension (428.2 ng/l, [77.8–1069.2] n = 38), despite an elevated trend in these CHD patients with hypertension (P = 0.0718, Figure 1C). The gene discussed is FGF21; the disease is hypertensive disorder.