On other hand, CHD subjects with diabetes (530.0 ng/l, [interquartile rang 75.6–1941.3], n = 61) had significantly higher serum FGF-21 levels (P = 0.034) than those of CHD subjects without diabetes (317.2 ng/l, [59.1–680.5], n = 74) (Figure 1B), consistent with the finding by Chen et al [25]. This evidence concerns the gene FGF21 and coronary artery disorder.