Kaplan-Meier analysis demonstrated a significant impact of well-known clinicopathologic prognostic parameters, such as serum AFP levels (P < 0.0001), tumor size (P < 0.0001), tumor multiplicity (P < 0.0001), clinical stage (P < 0.0001), vascular invasion (P < 0.0001), and relapse (P < 0.0001) on patients' survival (Table 3). The gene discussed is AFP; the disease is neoplasm.