The RUNX3-expressing HCC cell lines demonstrated enhanced serum starvation-induced apoptosis; the percentage of apoptotic cells determined by DAPI staining was 21 ± 2%, 25 ± 2%, 19 ± 1%, and 20 ± 2% in Hep3B, Huh7, HLE, and HLF cells, respectively (Figure 6B). The gene discussed is RUNX3; the disease is hepatocellular carcinoma.