CLMB and neoplasm: In univariate Cox regression analysis of several clinicopathological variables (age, sex, tumor size, number, grade, stage, intravesical therapy, and C16orf74 mRNA expression levels), age, intravesical therapy and C16orf74 mRNA expression levels were significant risk factors for progression (p = 0.031, p = 0.034 and p<0.001, respectively).