In that study, C16orf74 was one of eight candidate genes identified for predicting disease progression in NMIBC, suggesting a potential relationship between bladder cancer and C16orf74. In the current study, we assessed the relationship between C16orf74 and NMIBC outcomes using data from a previous study population as well as new cases, all with long-term follow-up. This evidence concerns the gene CLMB and urinary bladder carcinoma.