There was however a striking IL-2 response in both active and latent disease to Rv1986 pool 2 (795 SFC/106 PBMC, IQR 51–1428 in active infection; 1194 SFC/106 PBMC, IQR 862–1650 in latent infection, Figure 1C and D). The gene discussed is IL2; the disease is disease arising from reactivation of latent virus.