TLR5 and inflammatory bowel disease: For both the TLR5 SNPs C100T and T1844C, the T allele was significantly protective for IBD, and exerted a dominant effect (p<0.0001, OR = 0.19 [0.09–0.44, 95% CI]: p = 7e-04, OR = 0.25 [0.11–0.58, 95% CI], respectively; Table 6).