PDGFB and neoplasm: During investigations on the role of the long 3′UTR of PDGF-B mRNA in cell type-specific expression or deregulation of its expression in tumor cells, PC3 was observed to express the PDGF-B protein from the transfected pCMV-PDGF-B vector at 5–50-fold higher level compared to all other cell lines that were used.