Furthermore, statistical analysis demonstrated that miR-96 expression not only inversely correlated with FOXO3a (r = −0.7577, P<0.001) but also significantly correlated with the Ki-67 level (r = 0.7151, P<0.001) (Figure 6E), which further strengthened the notion that miR-96 mediates proliferation of breast cancer through suppression of the transcriptional factor FOXO3a. This evidence concerns the gene MKI67 and breast carcinoma.