FOXO3 and breast carcinoma: As shown in Figure 4D, ectopic expression of miR-96 in MCF-7 and ZR-75-30 breast cancer cells dramatically inhibited the GFP protein expression, but not the expression of GFP-γ-tubulin that was used as a control for transfection efficiency, suggesting that miR-96 specifically affected the FOXO3a-3′ UTR.