HTR1A and epilepsy: Bartmann et al used the 5HT1A receptor ligand [18F]MPPF (fluorine-18-labeled4-(2;-methoxyphenyl)-1-[2;-(N-2"-pirydynyl)-p fluorobenzamido]ethylpiperazine) to study brain uptake in a chronic rat model of epilepsy and found that tariquidar treatment increased the transport into and decreased the transport out from the brain more in AED non-responders compared to AED responder rats [58].