TIMP1 and Hepatic fibrosis: (ii) Fibrosis biomarkers: The Original ELF (European Liver Fibrosis) test is a panel of automated immunoassays to detect three markers of matrix turnover in serum: hyaluronic acid (HA), tissue inhibitor of metalloproteinase 1 (TIMP1) and aminoterminal peptide of pro-collagen III (P3NP), used in combination with age.86 The simplified ELF panel excludes age but has a similar diagnostic performance.