CDH1 and neoplasm: One possible treatment option for tumour therapy is to induce loss of E-cadherin function in the entire tumour cell mass (via soluble E-cadherin extracellular domain, nAb, or peptide inhibition) to provide a relatively homogenous population of cells where specific inhibition of proliferative pathways associated with the tumorigenic phenotype can be achieved (e.g., FGF signalling).