INS and chronic obstructive pulmonary disease: Adipose tissue expressions of proapoptotic CASP3 and Bax did not differ among cachectic, normal-weight, overweight, and obese patients with COPD (Table 4), and no relationships between insulin sensitivity and CASP3 or Bax expressions were observed (r = 0.162, P = .413; r = 0.122, P = .446, resp).